To provide an overview of our work, some selected publications are presented below. For a comprehensive list of publications, please see ORCID

Ausgewählte Publikationen:

Dashraath P, Alves MP, Schwartz DA, Nielsen-Saines K, and Baud D. Potential mechanisms of intrauterine transmission of monkeypox virus. Lancet Microbe, 2022. (Article)

Barut T, Halwe NJ, Taddeo A, Kelly JN, Schön J, Ebert N, Ulrich L, Devisme C, Steiner S, Trüeb BS, Hoffmann B, Berenguer Veiga I, Leborgne NGF, Moreira EA, Breithaupt A, Wylezich C, Höper D, Wernike K, Godel A, Thomann L, Flück V, Stalder H, Brügger M, Oliveira Esteves BI, Zumkehr B, Beilleau G, Kratzel A, Schmied K, Ochsenbein S, Lang RM, Wider M, Machahua C, Dorn P, Marti TM, Funke-Chambour M, Rauch A, Widera M, Ciesek S, Dijkman R, Hoffmann D, Alves MP, Benarafa C, Beer M, and Thiel V. The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Commun, 2022. (Article)

Wang L, Aguiar Moreira EA, Kempf G, Miyake Y, Oliveira Esteves BI, Fahmi A, Schaefer JV, Dreier B, Yamauchi Y, Alves MP, Plückthun A, and Matthias P. Disrupting the HDAC6-ubiquitin interaction impairs infection by influenza and Zika virus and cellular stress pathways. Cell Rep. 2022. (Article)

Fahmi A, Brügger M, Démoulins T, Zumkehr B, Oliveira Esteves BI, Bracher L, Wotzkow C, Blank F, Thiel V, Baud D, and Alves MP. SARS-CoV-2 can infect and propagate in human placenta explants. Cell Rep Med, 2021. (Article)

Brügger M, Démoulins T, Barut GT, Zumkehr B, Oliveira Esteves BI, Mehinagic K, Haas Q, Schögler A, Rameix-Welti MA, Eléouët JF, Moehrlen U, Marti TM, Schmid RA, Summerfield A, Posthaus H, Ruggli N, Hall SRR, and Alves MP. Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLOS Pathog, 2021. (Article)

Shrestha N, Gall FM, Mathieu C, Hierweger MM, Brügger M, Alves MP, Vesin J, Banfi D, Kalbermatter D, Horvat B, Chambon M, Turcatti G, Fotiadis D, Riedl R, and Plattet P. Highly potent host-specific small-molecule inhibitor of paramyxovirus and pneumovirus replication with high resistance barrier. mBio, 2021. (Article)

Démoulins T, Brügger M, Zumkehr B, Oliveira Esteves BI, Mehinagic K, Fahmi A, Borcard L, Taddeo A, Jandrasits D, Posthaus H, Benarafa C, Ruggli N, and Alves MP. The specific features of the developing T cell compartment of the neonatal lung are a determinant of respiratory syncytial virus immunopathogenesis. PLOS Pathog, 2021. (Article)

Schögler, A., Caliaro, O., Brügger, M., Oliveira Esteves, B.I., Nita, I., Gazdhar, A., Geiser, T., and Alves, M.P. Modulation of the unfolded protein response pathway as an antiviral approach in airway epithelial cells. Antiviral Res, 2019. (Article)

Vielle, N.J., García-Nicolás, O., Oliveira Esteves, B.I., Brügger, M., Summerfield, A., and Alves, M.P. The human upper respiratory tract epithelium is susceptible to flaviviruses. Front Microbiol, 2019. (Article)

García-Nicolás O, Braun RO, Milona P, Lewandowska M, Dijkman R, Alves MP, and Summerfield A. Targeting of the nasal mucosa by Japanese encephalitis virus for non-vector-borne transmission. J Virol, 2018. (Article)

Alves MP, Vielle NJ, Thiel V, and Pfaender S. Research models and tools for the identification of antivirals and therapeutics against Zika virus infection. Viruses, 2018. (Article)