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Selected Publications:

Démoulins T, Brügger M, Zumkehr B, Oliveira Esteves BI, Mehinagic K, Fahmi A, Borcard L, Taddeo A, Jandrasits D, Posthaus H, Benarafa C, Ruggli N, and Alves MP. The specific features of the developing T cell compartment of the neonatal lung are a determinant of respiratory syncytial virus immunopathogenesis. PLoS Pathog, 2021. (PubMed)

Usemann J, Alves MP, Ritz N, Latzin P, and Müller L. Age-dependent response of the human nasal epithelium to rhinovirus infection. Eur Respir J, 2020. (PubMed)

Wang L, Dorn P, Zeinali S, Froment L, Berezowska S, Kocher GJ, Alves MP, Brügger M, Esteves BIO, Blank F, Wotzkow C, Steiner S, Amacker M, Peng RW, Marti TM, Guenat OT, Bode PK, Moehrlen U, Schmid RA, and Hall SRR. CD90+ CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lung. Am J Physiol Lung Cell Mol Physiol, 2020. (PubMed)

Cabanelas E, Panadero R, Baumman A, Alves MP, Summerfield A, García-Dios D, Díaz P, Remesar S, Fernández G, Morrondo MP, Díez-Baños P, and López CM. Cytokine expression in bovine PBMC cultures stimulated with Hypoderma lineatum antigens. Vet Parasitol, 2020. (PubMed)

Beyeler S, Steiner S, Wotzkow C, Tschanz SA, Adhanom Sengal A, Wick P, Haenni B, Alves MP, von Garnier C, and Blank F. Multi-walled carbon nanotubes activate and shift polarization of pulmonary macrophages and dendritic cells in an in vivo model of chronic obstructive lung disease. Nanotoxicology, 2020. (PubMed)

Vielle, N.J., García-Nicolás, O., Oliveira Esteves, B.I., Brügger, M., Summerfield, A., and Alves, M.P. The human upper respiratory tract epithelium is susceptible to flaviviruses. Front Microbiol, 2019. (PubMed)

Schögler, A., Caliaro, O., Brügger, M., Oliveira Esteves, B.I., Nita, I., Gazdhar, A., Geiser, T., and Alves, M.P. Modulation of the unfolded protein response pathway as an antiviral approach in airway epithelial cells. Antiviral Res, 2019. (PubMed)

Alves MP, Vielle NJ, Thiel V, and Pfaender S. Research models and tools for the identification of antivirals and therapeutics against Zika virus infection. Viruses, 2018. (PubMed)

García-Nicolás O, Braun RO, Milona P, Lewandowska M, Dijkman R, Alves MP, and Summerfield A. Targeting of the nasal mucosa by Japanese encephalitis virus for non-vector-borne transmission. J Virol, 2018. (PubMed)

Tamò L, Hibaoui Y, Kallol S, Alves MP, Albrecht C, Hostettler K, Feki A, Rougier JS, Abriel H, Knudsen L, Gazdhar A, and Geiser T. Generation of an an alveolar epithelial type II cell line from induced pluripotent stem cells. Am J Respir Cell Mol Biol, 2018. (PubMed)

García-Nicolás O, V’kovski P, Vielle NJ, Ebert N, Züst R, Portmann J, Stalder H, Gaschen V, Vieyres G, Stoffel M, Schweizer M, Summerfield A, Engler O, Pietschmann T, Todt D, Alves MP, Thiel V, and Pfaender S. The small compound inhibitor K22 displays broad antiviral activity against different members of the Flaviviridae family and offers potential as pan-viral inhibitor. Antimicrob Agents Chemother, 2018. (PubMed)

Vielle NJ, Zumkehr B, García-Nicolás O, Blank F, Stojanov M, Musso D, Baud D, Summerfield A, and Alves MP. Silent infection by African and Asian strains of Zika virus in human dendritic cells. Sci Rep, 2018. (PubMed)

Schögler A, Blank F, Brügger M, Beyeler S, Tschanz S, Casaulta C, Jung A, Moeller A, and Alves MP. Characterization of pediatric cystic fibrosis airway epithelial cell cultures at the air-liquid interface obtained by non-invasive nasal cytology brush sampling. Respir Res, 2017. (PubMed)

Behrendt P, Perin, P, Menzel N, Banda D, Pfaender S, Alves MP, Thiel V, Meulemann P, Colpitts CC, Schang LM, Vondran FWR, Anggakusuma, Manns MP, Steinmann E, and Pietschmann T. Pentagalloylglucose, a highly bioavailable polyphenolic compound present in Cortex moutan, efficiently blocks hepatitis C virus entry. Antiviral Res, 2017. (PubMed)

Baud D, Musso D, Vouga M, Alves MP, and Vulliemoz N.  Zika virus: a new treath to human reproduction. Am J Reprod Immunol, 2017. (PubMed)

Siddharta A, Pfaender S, Vielle NJ, Dijkman R, Friesland M, Becker B, Yang J, Engelmann M, Todt D, Windisch M, Brill FH, Steinmann J, Steinmann J, Becker S, Alves MP, Pietschmann T, Eickmann M, Thiel V, Steinmann E. Virucidal activity of WHO-recommended formulations against enveloped viruses including Zika, Ebola and emerging Coronaviruses. J Infect Dis, 2017. (PubMed)

Pfaender S, Vielle NJ, Ebert N, Steinmann E, Alves MP, and Thiel VE. Inactivation of Zika Virus in human breast milk by prolonged storage or pasteurization. Virus Res, 2017. (PubMed)

Baud D, Gérardin P, Merriam A, Alves MP, Musso D, Genton B, Panchaud A. Harness shared data in international Zika registry. BMJ, 2016. (PubMed)

Vouga M, Alves MP, Eperon I, Rochat L, Sahli R, Musso D, and Baud D. Zika virus: from research to vaccine. Rev Med Suisse, 2016. (PubMed)

Schögler A, Muster RJ, Kieninger E, Casaulta C, Tapparel C, Jung A, Möller A, Geiser T, Regamey N, and Alves MP. Vitamin D represses rhinovirus replication in cystic fibrosis cells by inducing LL-37. Eur Respir J, 2016. (PubMed)

Alves MP, Schögler A, Ebener S, Vielle NJ, Casaulta C, Jung A, Moeller A, Geiser T, and Regamey N. Comparison of innate immune responses towards rhinovirus infection of primary nasal and bronchial epithelial cells. Respirology, 2016. (PubMed)

Schögler A, Stokes AB, Casaulta C, Regamey N, Edwards MR, Johnston SL, Jung A, Möller A, Geiser T, and Alves MP. Interferon response of the cystic fibrosis bronchial epithelium to major and minor group rhinovirus infection. J Cyst Fibrosis, 2016. (PubMed)

Müller L, Mack I, Tapparel C, Kaiser L, Alves MP, Kieninger E, Frey U, Regamey N, and Latzin P. Human rhinovirus types and association with respiratory symptoms during the first year of life. Ped Infect Dis J, 2015. (PubMed)

Schögler A, Kopf BS, Edwards MR, Johnston SL, Casaulta C, Kieninger E, Jung A, Möller A, Geiser T, Regamey N, and Alves MP. Novel antiviral properties of azithromycin in cystic fibrosis airway epithelial cells. Eur Respir J, 2015. (PubMed)

Tang AC, Turvey SE, Alves MP, Regamey N, Tümmler B, and Hartl, D. Current concepts: host-pathogen interactions in cystic fibrosis lung disease. Eur Respir Rev, 2014. (PubMed)

Stokes AB, Kieninger E, Schögler A, Kopf BS, Casaulta C, Geiser T, Regamey N, and Alves MP. Comparison of three different brushing techniques to isolate and culture primary nasal epithelial cells from human subjects. Exp Lung Res, 2014. (PubMed)

Cangiano G, Proietti E, Kronig MN, Kieninger E, Sadeghi CD, Gorgievski M, Barbani MT, Midulla F, Kaiser L, Tapparel C, Alves MP, and Regamey N. Lactate dehydrogenase concentration in nasal wash fluid indicates severity of rhinovirus-induced wheezy bronchitis in preschool children. Ped infect Dis J, 2014. (PubMed)

Kieninger E, Singer F, Tapparel C, Alves MP, Latzin P, Casaulta C, Tan HL, Bossley C, Bush A, Davies JC, Kaiser L, and Regamey N. High rhinovirus burden in lower airways of children with cystic fibrosis. Chest, 2013. (PubMed)

Kieninger E, Vareille M, Kopf BS, Blank F, Alves MP, Gisler FM, Latzin P, Casaulta C, Geiser T, Johnston SL, Edwards MR, and Regamey N. Lack of an exaggerated inflammatory response upon virus infection in cystic fibrosis. Eur Respir J, 2012. (PubMed)