Publications 2020 (IVI)

Ancar, R., Li, Y., Kindler, E., Cooper, D.A., Ransom, M., Thiel, V., Weiss, S.R., Hesselberth, J.R., and Barton, D.J. (2020) Physiologic RNA targets and refined sequence specificity of coronavirus EndoU. RNA 26:12, 1976-1999. (PubMed) (article)

Auray, G., Talker, S.C., Keller, I., Python, S., Gerber, M., Liniger, M., Ganges, L., Bruggmann, R., Ruggli, N., and Summerfield, A. (2020) High-resolution profiling of innate immune responses by porcine dendritic cell subsets in vitro and in vivo. Frontiers in Immunology 11, 1429. (PubMed) (article)

Barut, G.T.#, Lischer, H.E.L., Bruggmann, R., Summerfield, A., and Talker, S.C. (2020) Transcriptomic profiling of bovine blood dendritic cells and monocytes following toll-like receptor stimulation. European Journal of Immunology 50:11, 1691-1711. (PubMed) (article)

Beyeler, S.#, Steiner, S., Wotzkow, C., Tschanz, S.A., Adhanom Sengal, A., Wick, P., Haenni, B., Alves, M.P., von Garnier, C., and Blank, F. (2020) Multi-walled carbon nanotubes activate and shift polarization of pulmonary macrophages and dendritic cells in an in vivo model of chronic obstructive lung disease. Nanotoxicology 14:1, 77-96. (PubMed) (article)

Blockus, S., Sake, S.M., Wetzke, M., Grethe, C., Graalmann, T., Pils, M., Le Goffic, R., Galloux, M., Prochnow, H., Rox, K., Hüttel, S., Rupcic, Z., Wiegmann, B., Dijkman, R., Rameix-Welti, M.A., Eléouët, J.F., Duprex, W.P., Thiel, V., Hansen, G., Brönstrup, M., Haid, S., and Pietschmann, T. (2020) Labyrinthopeptins as virolytic inhibitors of respiratory syncytial virus cell entry. Antiviral Research 177, 104774. (PubMed) (article)

Cabanelas, E., Panadero, R., Baumman, A., Alves, M.P., Summerfield, A., García-Dios, D., Díaz, P., Remesar, S., Fernández, G., Morrondo, M.P., Díez-Baños, P., and López, C.M. (2020) Cytokine expression in bovine PBMC cultures stimulated with Hypoderma lineatum antigens. Veterinary Parasitology 283, 109165. (PubMed) (article)

Cong, Y., Ulasli, M., Schepers, H., Mauthe, M., V'kovski, P., Kriegenburg, F., Thiel, V., de Haan, C.A.M., and Reggiori, F. (2020) Nucleocapsid protein recruitment to replication-transcription complexes plays a crucial role in coronaviral life cycle. Journal of Virology 94:4, e01925-19. (PubMed) (article)

Eiden, S., Dijkman, R., Zell, R., Fuchs, J., and Kochs, G. (2020) Using a mouse-adapted A/HK/01/68 influenza virus to analyse the impact of NS1 evolution in codons 196 and 231 on viral replication and virulence. Journal of General Virology 101:6, 587-598. (PubMed) (article)

Eschbaumer, M., Vögtlin, A., Paton, D.J., Barnabei, J.L., Sanchez-Vazquez, M.J., Pituco, E.M., Rivera, A.M., O'Brien, D., Nfon, C., Brocchi, E., Bakkali Kassimi, L., Lefebvre, D.J., Navarro López, R., Maradei, E., Duffy, S.J., Loitsch, A., De Clercq, K., King, D.P., Zientara, S., Griot, C., and Beer, M. (2020) Non-discriminatory exclusion testing as a tool for the early detection of foot-and-mouth disease incursions. Frontiers in Veterinary Science 7, 552670. (PubMed) (article)

Ganges, L., Crooke, H.R., Bohórquez, J.A., Postel, A., Sakoda, Y., Becher, P., and Ruggli, N. (2020) Classical swine fever virus: the past, present and future. Virus Research 289, 198151. (PubMed) (article)

Gasbarri, M., V'kovski, P., Torriani, G., Thiel, V., Stellacci, F., Tapparel, C., and Cagno, V. (2020) SARS-CoV-2 inhibition by sulfonated compounds. Microorganisms 8:12, 1894. (PubMed) (article)

Gultom, M.#, Laloli, L.#, and Dijkman, R. (2020) Well-differentiated primary mammalian airway epithelial cell cultures. Methods in Molecular Biology 2203, 119-134. (PubMed) (article)

Hidber, T., Pauli, U., Steiner, A., and Kuhnert, P. (2020) In vitro and ex vivo testing of alternative disinfectants to currently used more harmful substances in footbaths against Dichelobacter nodosus. PLoS ONE 15:2, e0229066. (PubMed) (article)

Hilty, M., Wüthrich, T.M.#, Godel, A., Adelfio, R., Aebi, S., Burgener, S.S., Illgen-Wilcke, B., and Benarafa, C. (2020) Chronic cigarette smoke exposure and pneumococcal infection induce oropharyngeal microbiota dysbiosis and contribute to long-lasting lung damage in mice. Microbial Genomics 6:12, e000485. (PubMed) (article)

Holwerda, M.#, V'Kovski, P., Wider, M., Thiel, V., and Dijkman, R. (2020) Identification of an antiviral compound from the pandemic response box that efficiently inhibits SARS-CoV-2 infection in vitro. Microorganisms 8:12, 1872. (PubMed) (article)

Hufsky, F., Beerenwinkel, N., Meyer, I.M., Roux, S., Cook, G.M., Kinsella, C.M., Lamkiewicz, K., Marquet, M., Nieuwenhuijse, D.F., Olendraite, I., Paraskevopoulou, S., Young, F., Dijkman, R., Ibrahim, B., Kelly, J., Le Mercier, P., Marz, M., Ramette, A., and Thiel, V. (2020) The International Virus Bioinformatics Meeting 2020. Viruses-Basel 12:12, 1398. (PubMed) (article)

Hüppi, L., Ruggli, N., Python, S., Hoop, R., Albini, S., Grund, C., and Vögtlin, A. (2020) Experimental pigeon paramyxovirus-1 infection in chicken: evaluation of infectivity, clinical and pathological manifestations and diagnostic methods. Journal of General Virology 101:2, 156-167. (PubMed) (article)

Itakura, Y., Matsuno, K., Ito, A., Gerber, M., Liniger, M., Fujimoto, Y., Tamura, T., Kameyama, K.I., Okamatsu, M., Ruggli, N., Kida, H., and Sakoda, Y. (2020) A cloned classical swine fever virus derived from the vaccine strain GPE- causes cytopathic effect in CPK-NS cells via type-I interferon-dependent necroptosis. Virus Research 276, 197809. (PubMed) (article)

Jores, J., Baldwin, C., Blanchard, A., Browning, G.F., Colston, A., Gerdts, V., Goovaerts, D., Heller, M., Juleff, N., Labroussaa, F., Liljander, A., Muuka, G., Nene, V., Nir-Paz, R., Sacchini, F., Summerfield, A., Thiaucourt, F., Unger, H., Vashee, S., Wang, X., and Salt, J. (2020) Contagious bovine and caprine pleuropneumonia: a research community's recommendations for the development of better vaccines. npj Vaccines 5, 66. (PubMed) (article)

Kauer, R.V., Koch, M.C., Schönecker, L., Becker, J., Holwerda, M.#, Glaus, A.N., Hierweger, M.M., Werder, S., Dijkman, R., Meylan, M., and Seuberlich, T. (2020) Fecal shedding of bovine astrovirus CH13/NeuroS1 in veal calves. Journal of Clinical Microbiology 58:5, e01964-19. (PubMed) (article)

Kratzel, A.#, Steiner, S.#, Todt, D., V'kovski, P., Brueggemann, Y., Steinmann, J., Steinmann, E., Thiel, V., and Pfaender, S. (2020) Temperature-dependent surface stability of SARS-CoV-2. Journal of Infection 81:3, 474-476. (PubMed) (article)

Kratzel, A.#, Todt, D., V'kovski, P., Steiner, S.#, Gultom, M.#, Thao, T.T.N.#, Ebert, N., Holwerda, M.#, Steinmann, J., Niemeyer, D., Dijkman, R., Kampf, G., Drosten, C., Steinmann, E., Thiel, V., and Pfaender, S. (2020) Inactivation of severe acute respiratory syndrome coronavirus 2 by WHO-recommended hand rub formulations and alcohols. Emerging Infectious Diseases 26:7, 1592-1595. (PubMed) (article)

Leborgne, N.G.F.#, Taddeo, A., Freigang, S., and Benarafa, C. (2020) Serpinb1a is dispensable for the development and cytokine response of invariant natural killer T cell subsets. Frontiers in Immunology 11, 562587. (PubMed) (article)

Meng, X.J., and Thiel, V. (2020) Emerging and re-emerging porcine viruses [editorial]. Virus Research 290, 198198. (PubMed) (article)

Meyer, B., Torriani, G., Yerly, S., Mazza, L., Calame, A., Arm-Vernez, I., Zimmer, G., Agoritsas, T., Stirnemann, J., Spechbach, H., Guessous, I., Stringhini, S., Pugin, J., Roux-Lombard, P., Fontao, L., Siegrist, C.A., Eckerle, I., Vuilleumier, N., Kaiser, L., for the Geneva Center for Emerging Viral Diseases (2020) Validation of a commercially available SARS-CoV-2 serological immunoassay. Clinical Microbiology and Infection 26:10, 1386-1394. (PubMed) (article)

Moreno, H., Rastrojo, A., Pryce, R., Fedeli, C., Zimmer, G., Bowden, T.A., Gerold, G., and Kunz, S. (2020) A novel circulating tamiami mammarenavirus shows potential for zoonotic spillover. PLoS Neglected Tropical Diseases 14:12, e0009004. (PubMed) (article)

Nardelli, S., Bettini, A., Capello, K., Bertoni, G., and Tavella, A. (2020) Eradication of caprine arthritis encephalitis virus in the goat population of South Tyrol, Italy: analysis of the tailing phenomenon during the 2016-2017 campaign. Journal of Veterinary Diagnostic Investigation 32:4, 589-593. (PubMed) (article)

Pfaender, S., Mar, K.B., Michailidis, E., Kratzel, A.#, Boys, I.N., V’kovski, P., Fan, W., Kelly, J.N., Hirt, D., Ebert, N., Stalder, H., Kleine-Weber, H., Hoffmann, M., Heinrich Hoffmann, H., Saeed, M., Dijkman, R., Steinmann, E., Wight-Carter, M., McDougal, M.B., Hanners, N.W., Pöhlmann, S., Gallagher, T., Todt, D., Zimmer, G., Rice, C.M., Schoggins, J.W., and Thiel, V. (2020) LY6E impairs coronavirus fusion and confers immune control of viral disease. Nature Microbiology 5:11, 1330-1339. (PubMed) (article)

Quan, T.M., Thao, T.T.N.#, Duy, N.M., Nhat, T.M., and Clapham, H. (2020) Estimates of the global burden of Japanese encephalitis and the impact of vaccination from 2000-2015. eLife 9, e51027. (PubMed) (article)

Saade, G., Deblanc, C., Bougon, J., Marois-Créhan, C., Fablet, C., Auray, G., Belloc, C., Leblanc-Maridor, M., Gagnon, C.A., Zhu, J., Gottschalk, M., Summerfield, A., Simon, G., Bertho, N., and Meurens, F. (2020) Coinfections and their molecular consequences in the porcine respiratory tract. Veterinary Research 51:1, 80. (PubMed) (article)

Schubert, K., Karousis, E.D., Jomaa, A., Scaiola, A., Echeverria, B., Gurzeler, L.A., Leibundgut, M., Thiel, V., Mühlemann, O., and Ban, N. (2020) SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation. Nature Structural & Molecular Biology 27, 959-966. (PubMed) (article)

Thao, T.T.N.#, Labroussaa, F., Ebert, N., Jores, J., and Thiel, V. (2020) In-yeast assembly of coronavirus infectious cDNA clones using a synthetic genomics pipeline. Methods in Molecular Biology 2203, 167-184. (PubMed) (article)

Thao, T.T.N.#, Labroussaa, F., Ebert, N., V’kovski, P., Stalder, H.P., Portmann, J., Kelly, J., Steiner, S.#, Holwerda, M.#, Kratzel, A.#, Gultom, M.#, Schmied, K., Laloli, L.#, Hüsser, L., Wider, M., Pfaender, S., Hirt, D., Cippà, V., Crespo-Pomar, S., Schröder, S., Muth, D., Niemeyer, D., Corman, V., Müller, M.A., Drosten, C., Dijkman, R., Jores, J., and Thiel, V. (2020) Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform. Nature 582:7813, 561-565. (PubMed) (article) (media release)

Thiel, V. (2020) Viral RNA in an m6A disguise. Nature Microbiology 5:4, 531-532. (PubMed) (article)

Thiel, V., and Jores, J. (2020) Ein Klon geht um die Welt. Pipette 2, 16-17. (article [in German])

Trueeb, B.S., Braun, R.O.#, Auray, G., Kuhnert, P., and Summerfield, A. (2020) Differential innate immune responses induced by Mycoplasma hyopneumoniae and Mycoplasma hyorhinis in various types of antigen presenting cells. Veterinary Microbiology 240, 108541. (PubMed) (article)

Usemann, J., Alves, M.P., Ritz, N., Latzin, P., and Müller, L. (2020) Age-dependent response of the human nasal epithelium to rhinovirus infection. European Respiratory Journal 56:5, 2000877. (PubMed) (article)

Vizcaíno Revés, N., Mogel, H.M., Stoffel, M., Summerfield, A., and Forterre, F. (2020) Polarization of macrophages in epidural inflammation induced by canine intervertebral disc herniation. Frontiers in Veterinary Science 7, 32. (PubMed) (Artikel)

V'kovski, P., Steiner, S.#, and Thiel, V. (2020) Proximity labeling for the identification of coronavirus-host protein interactions. Methods in Molecular Biology 2203, 187-204. (PubMed) (article)

Wang, L., Dorn, P., Zeinali, S., Froment, L., Berezowska, S., Kocher, G.J., Alves, M.P., Brügger, M.#, Esteves, B.I.O., Blank, F., Wotzkow, C., Steiner, S., Amacker, M., Peng, R.W., Marti, T.M., Guenat, O.T., Bode, P.K., Moehrlen, U., Schmid, R.A., and Hall, S.R.R. (2020) CD90+CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lung. American Journal of Physiology - Lung Cellular and Molecular Physiology 318:4, L813-L830. (PubMed) (article)

Wang, M., Liniger, M., Muñoz-González, S., Bohórquez, J.A., Hinojosa, Y.#, Gerber, M., López-Soria, S., Rosell, R., Ruggli, N., and Ganges, L. (2020) A poly-uridine insertion in the 3'-untranslated region of classical swine fever virus activates immunity and reduces viral virulence in piglets. Journal of Virology 94:2, e01214-19. (PubMed) (article)

Warryn, L., Dangy, J.P., Gersbach, P., Gehringer, M., Schäfer, A., Ruf, M.T., Ruggli, N., Altmann, K.H., and Pluschke, G. (2020) Development of an ELISA for the quantification of mycolactone, the cytotoxic macrolide toxin of Mycobacterium ulcerans. PLoS Neglected Tropical Diseases 14:6, e0008357. (PubMed) (article)

Zaugg, I., Herrmann, N., and Ottiger, H. (2020) Vaccinovigilance: Reports of adverse reactions in the year 2019 [in German]. Schweizer Archiv für Tierheilkunde 162:10, 617-624. (PubMed) (article)

Zettl, F., Meister, T.L., Vollmer, T., Fischer, B., Steinmann, J., Krawczyk, A., V'kovski, P., Todt, D., Steinmann, E., Pfaender, S., and Zimmer, G. (2020) Rapid quantification of SARS-CoV-2-neutralizing antibodies using propagation-defective vesicular stomatitis virus pseudotypes. Vaccines (Basel) 8:3, 386. (PubMed) (article)

Zhou, H., Møhlenberg, M., Terczyńska-Dyla, E., Winther, K.G., Hansen, N.H., Vad-Nielsen, J., Laloli, L.#, Dijkman, R., Nielsen, A.L., Gad, H.H., and Hartmann, R. (2020) The IFNL4 gene is a non-canonical interferon gene with a unique but evolutionarily conserved regulation. Journal of Virology94:5, e01535-19. (PubMed) (article)

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