Summerfield Lab

Our general aim is to understand the functioning of the immune system in pigs and other veterinary species. Our laboratory is focusing on phagocytes, in particular dendritic cells and macrophages but also neutrophils. These represent central cells in the innate immune response and are also essential to induce adaptive immune responses. With the tools available we are developing new vaccine adjuvants and vectors designed to induce specific types of immune responses in pigs to improve antibody and T-lymphocyte responses, both systemically and at mucosal surfaces. In addition, our research aims to understand the mechanisms of how viruses induce disease and evade the host immune response with a focus on phagocyte-pathogen interaction.